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Extra info for High Density Lipoproteins: From Biological Understanding to Clinical Exploitation (Handbook of Experimental Pharmacology)
8 Introduction The management of most cases of poisoning is symptomatic and supportive. Gastric decontamination with activated charcoal or gastric lavage is usually only worthwhile within one hour of ingestion (AACT/EAPCCT, 1997a,b). Activated charcoal is made from organic material such as coconut shells, peat or wood that has been burned and then heated to a very high temperature in steam, air or carbon dioxide. The result is a finely divided powder with an extensive pore structure and a large surface area (1,000 m2/g) that can adsorb a wide range of substances.
1,2,4-Benzenetriol (hydroxyquinol, 1,2,4-trihydroxybenzene) This compound is not found in the urine of individuals with no occupational exposure to benzene. There is correlation between exposure and the urinary concentration of 1,2,4-benzenetriol. , 1989b). Consequently 1,2,4-benzenetriol is not recommended as a biomarker for benzene exposure. • Benzene in blood In the study by Perbellini et al. (1988) the benzene exposure concentration significantly correlated with the blood benzene concentration but not with the concentration in the breath.
Van Nieuwenhuyse (Bte 6), B-1160 Brussels, Belgium. org REFERENCES ACGIH. 2000 Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Limits. American Conference of Governmental Industrial Hygienists. AACT/EAPCCT. 1997a American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. Position statement: gastric lavage. Clin Toxicol 35 (7):711-719. AACT/EAPCCT. 1997b American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.
High Density Lipoproteins: From Biological Understanding to Clinical Exploitation (Handbook of Experimental Pharmacology)