By Ingo Weisse (auth.), Ingo Weisse, Otto Hockwin, Keith Green, Ramesh C. Tripathi (eds.)

ISBN-10: 1461357691

ISBN-13: 9781461357698

ISBN-10: 1461518873

ISBN-13: 9781461518877

On behalf of the editorial board and the organizing committee of the 4th congress of the overseas Society of Ocular Toxicology (I SOT), held in AnnecyNeyrier du Lac, France, October nine -13, 1994, we're happy to give to the ocular toxicology group this listed quantity of our congress lawsuits. The 4th congress used to be designed basically to facilitate and replace the data in ocular electrophysiology and ocular pharmacokinetics, in either the medical and preclinical facets. the end result of this 4th congress, proven during this quantity, is an invaluable contribution to the meth­ odology in either fields and may confidently help in the evaluate and interpretation of ocular findings recorded in animal experiences on medications and different chemical substances, as a way to defend human wellbeing and fitness. certainly, paintings at the mechanisms of ocular toxicology within the means of pharmaceutical improvement needs to proceed and those complaints, embodying the offered papers, will upload to the knowledge base. The editors, the congress organizing committee and the contributors of the foreign Society of Ocular Toxicology thank the audio system who gave their time, wisdom, and services to help us during this venture. the subsequent manuscripts comprise the most substance of every of the platform displays and, from time to time, even more. additionally, our thank you visit all of the individuals coming from more than a few history- regulatory, educational and business -for their recognition and perfect contributions throughout the discussion.

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4 ~ 8 ~ 12 16 Figure 1. Effects of an intravitreal injection of 200 JIg gentamidn on the ERG of a pigmented rabbit. The c-wave was abolished 1 to 2 weeks after gentamicin injectiml. The right and left columns show responses respectively from the antimicrobial-injected eye and the control fellow eye injected only with a vehicle in Figures 1 and 3. Stimnlus intensity was 5 lux at the cornea Rectangnlar traces at thc bottom indicate the onset (upward dilection) and offset (downward deflection) of stimnlus light in Figures 1, 2, 3 and 5.

Doc. Ophthal. 83: 175-180. 23 Rudolph, G. , and Bonaventure, N. 1990. EOG and ERG modifications induced in the chicken eye after blockade of catecholamine and 5-hydroxytryptamine biosynthesis. Doc. Ophtha!. ']i: 47-53. , and Bonaventure, N. 1989. Electrooculographic study in the chicken after treatment with neurotoxin 6-hydroxydopamine. Doc. Ophtha!. 72: 83-91. A. 1994. Objective assessment of retinal function. A. B. Sanders Co. p 1195-1196. L. 1988. Diurnal rhythm in the electroretinogram of the Royal College of Surgeons (RCS) pigmented rat.

Photopic c-wave in the chicken ERG: sensitivity to sodium azide, epinephrine, sodium iodate, barbiturates, and other general anesthetics. Doc. Oohthal. 60: 407-412. , and Shiromani, P. 1991. Cholinergic antagonists and REM sleep generation. Brain Res. 543: 175-179. , and Yang, S. 1990. lI§i I Ko Ta Hsueh Hsueh Pao. 21: 394-397. , and Hara, 1. 1990. Electroretinographic changes induced by organophosphorus pesticides in rats. J. Tox. Sci. 15: 87-95. , and Dempsey, l,A. 1993. Effects ofrapid·eye·movement sleep on the apneic threshold in dogs.

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Ocular Toxicology by Ingo Weisse (auth.), Ingo Weisse, Otto Hockwin, Keith Green, Ramesh C. Tripathi (eds.)


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