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Extra resources for Science (Vol. 314, No. 5806,15 December 2006)

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Passed overwhelmingly by the House in September, the bill contained a 5%-a-year boost for NIH and would have required the common fund to get half of any NIH increase. 3% of NIH’s $28 billion budget. Biomedical lobbyists say they much prefer the Senate version that prevailed. The House bill would have restricted the ability of appropriators to target spending, notes Jon Retzlaff of the Federation of American Societies for Experimental Biology in Bethesda, Maryland. “If they wanted to add $100 million for some research program, they would need to give NIH $200 million,” he says.

That would genand tiny ice particles soared hundreds of kilo- erate vapor and frozen droplets that jet out meters above the airless moon from a rela- from crevices in the moon’s icy crust. tively “warm” (145 kelvin) spot on the surThere was one snag, says Susan Kieffer, a face. Cassini team members concluded in one geological fluid dynamicist at the University paper that liquid water as little as 7 meters of Illinois, Urbana-Champaign, who has studied the dynamics of Old Faithful. On reading an accompanying Cassini paper, Kieffer and her colleagues learned that the spacecraft’s mass spectrometer had detected considerable amounts of carbon dioxide, methane, and nitrogen in the plume.

And at the neuroscience meeting, Stanford applied physicist Mark Schnitzer showed off a microendoscope small enough to fit on the head of a freely moving mouse. The thumbnail-sized device weighs less than 4 grams, and its fiberoptic probes can reach any structure in the mouse brain. So far, Schnitzer’s group has been using the device for imaging cells labeled with fluorescent dyes, but he says there’s no reason it couldn’t also be used to stimulate light-sensitive neurons. Far in the future, it’s conceivable that fiberoptic light stimulation could replace deep brain stimulation via electrodes, a method currently under investigation for Parkinson’s disease, depression, epilepsy, and other disorders.

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Science (Vol. 314, No. 5806,15 December 2006)

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