By Luis M. Botana

ISBN-10: 0824789563

ISBN-13: 9780824789565

The previous few years have caused many alterations within the box of marine and freshwater pollution, with advances in analytical know-how and the conclusion that those pollution are a world factor. providing an entire reference advisor, Seafood and Freshwater pollution: Pharmacology, body structure, and Detection, 3rd Edition addresses all points of the social and medical impact of phytotoxins, from laws and tracking to new drug improvement. overlaying many new themes, the e-book examines 3 major features: tracking of poisons; chemical, mechanistic, and toxicological variety; and detection technologies.

New to this edition:

  • 35 new chapters and five up to date chapters
  • A concentrate on cutting-edge methodology
  • Coverage of latest applied sciences to domesticate algae and to spot, isolate, and quantify toxins
  • Regulatory changes
  • Climate swap evidence
  • Expanded info on toxicology

Part I of the publication comprises an summary and studies common matters relating to toxin detection, ecology, and variety, and results of weather swap. half II covers affects of poisons relating to epidemiology, toxicology, economics, and surveillance. half III explores to be had detection applied sciences, resembling useful assays, biosensors, mass spectrometry, nanotechnology, and extra. furthermore, typical reference fabrics for pollution are mentioned. elements IV to VI supply special descriptions of toxin chemical range, organic resources, and modes of motion. half VII addresses using pollutants as beginning issues for healing medicines for melanoma, neurological issues, and for novel antibiotics.

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Additional resources for Seafood and freshwater toxins: pharmacology, physiology, and detection

Example text

The toxins responsible for NSP are a suite of ladder-like polycyclic ether toxins collectively called brevetoxins (PbTx, for Ptychodiscus brevis, more recently restored to its earlier taxonomic designation, Gymnodinium breve) (Figure 4). Brevetoxin congeners fall into two types based on backbone structure, the brevetoxin B backbone (type 1) and brevetoxin A backbone (type 2). The type 1 congeners are the most abundant in nature, with PbTx-2 and PbTx3 being the most prevelant in G. breve. Although the ring systems in the middle of the molecules differ somewhat, type 1 and type 2 toxins share a lactone in the A ring (‘‘head’’) and a conserved structure on the ‘‘tail’’ ring, both of which are required for their toxicity (26).

Identification of okadaic acid as a toxic component of a marine dinoflagellate Prorocentrum lima. Bull Jpn Soc Sci Fish 48:69–72, 1982. 50. K Tachibana, PJ Scheuer, Y Tsukitani, H Kikuchi, DV Engen, J Clardy, Y Gopichand, FJ Schmitz. Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria. J Am Chem Soc 103:2469–2471, 1981. 51. T Hu, J Doyle, D Jackson, J Marr, E Nixon, S Pleasance, MA Quilliam, JA Walter, JLC Wright. Isolation of a new diarrhetic shellfish poison from Irish mussels.

M Fukui, M Murata, A Inoue, M Gawel, T Yasumoto. Occurrence of palytoxin in the trigger fish Melichthys vidua. Toxicon 25:1121–1124, 1987. 34. T Yasumoto, D Yasumura, Y Ohizumi. Palytoxin in two species of xanthid crab from the Philippines. Agric Biol Chem 50:593–598, 1986. 35. AC Alcala, LC Alcala, JS Garth, D Yasumura, T Yasumoto. Human fatality due to ingestion of the crab Demania reynaudii that contained a palytoxin-like toxin. Toxicon 26:105–107, 1988. 36. Y Onuma, M Satake, T Ukena, J Roux, S Chanteau, N Rasolofonirina, M Ratsimaloto, H Naoki, T Yasumoto.

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Seafood and freshwater toxins: pharmacology, physiology, and detection by Luis M. Botana

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