By Maeve McParland, Nicola Bates

ISBN-10: 1859572960

ISBN-13: 9781859572962

ISBN-10: 1859573398

ISBN-13: 9781859573396

Solvents were the reason for occupational illnesses for a few years. employees were uncovered via dermis touch, by way of inhaling vapours, by way of splashes within the eye and, in severe circumstances, by means of ingestion. This booklet examines the scientific results of publicity to diversified solvents, fairly within the workplace.

The authors have tested fabric from key scientific and toxicological libraries, books, databases and their very own case experiences, to discover the most important results of solvent publicity. they've got long past again to unique case studies to make sure proof. the knowledge is summarised right here in ordered sections, together with melanoma inflicting job, epidermis and eye publicity results, inhalation results, reproductive results and strength genetic results. either acute (short-term) and protracted (long-term) exposures are reviewed. Glycol ethers and esters are coated in a single bankruptcy, different universal solvents are reviewed in person chapters.

A very worthy part on first relief is integrated, with precautions to be taken to prevent rescuers being affected.

Medical execs will locate worthy information regarding antidotes, checks for publicity, and medical institution administration of affected patients.

A word list of clinical phrases is incorporated to aid non-medical readers in knowing the text.

Key features

  • Chapters divided into concise sections
  • Useful precis first and foremost of every chapter
  • Synonyms and id numbers to facilitate solvent identification
  • Physical and chemical properties
  • Occupational publicity limits
  • Biomonitoring
  • Toxicology
  • Hospital management
  • Antidotes
  • Very good referenced
  • Glossary of clinical terms
  • Useful record of scientific abbreviations and acronyms
  • Index contains CAS, EINECS and RTECS numbers

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Extra resources for Toxicology of Solvents

Example text

8 Introduction The management of most cases of poisoning is symptomatic and supportive. Gastric decontamination with activated charcoal or gastric lavage is usually only worthwhile within one hour of ingestion (AACT/EAPCCT, 1997a,b). Activated charcoal is made from organic material such as coconut shells, peat or wood that has been burned and then heated to a very high temperature in steam, air or carbon dioxide. The result is a finely divided powder with an extensive pore structure and a large surface area (1,000 m2/g) that can adsorb a wide range of substances.

1,2,4-Benzenetriol (hydroxyquinol, 1,2,4-trihydroxybenzene) This compound is not found in the urine of individuals with no occupational exposure to benzene. There is correlation between exposure and the urinary concentration of 1,2,4-benzenetriol. , 1989b). Consequently 1,2,4-benzenetriol is not recommended as a biomarker for benzene exposure. • Benzene in blood In the study by Perbellini et al. (1988) the benzene exposure concentration significantly correlated with the blood benzene concentration but not with the concentration in the breath.

Van Nieuwenhuyse (Bte 6), B-1160 Brussels, Belgium. org REFERENCES ACGIH. 2000 Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Limits. American Conference of Governmental Industrial Hygienists. AACT/EAPCCT. 1997a American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. Position statement: gastric lavage. Clin Toxicol 35 (7):711-719. AACT/EAPCCT. 1997b American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.

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Toxicology of Solvents by Maeve McParland, Nicola Bates


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