By Gary West, Darryl Heard, Nigel Caulkett

ISBN-10: 0470376473

ISBN-13: 9780470376478

ISBN-10: 0813825660

ISBN-13: 9780813825663

Zoo Animal and natural world Immobilization and Anesthesia, moment Edition is an absolutely up to date and revised model of the 1st finished reference on anesthetic recommendations in captive and free-ranging flora and fauna. Now together with  increased insurance of avian and aquatic species, this exhaustive source offers details at the complete diversity of zoo and natural world species. overlaying subject matters starting from tracking and box anesthesia to CPR and euthanasia, the center of the e-book is dedicated to fifty three species-specific chapters delivering a wealth of knowledge on little-known and customary zoo and natural world animals alike.

as well as new species chapters, the recent variation brings a brand new specialize in discomfort administration, together with continual  discomfort, and additional info on species-specific body structure. Chapters on airway administration, tracking, emergency therapeutics, and box strategies are all considerably accelerated besides. This replace to Zoo Animal and natural world Immobilization and Anesthesia is a useful addition to the library of all zoo and natural world veterinarians.

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The COX-1 preferential NSAIDs are contraindicated in animals with spinal injury (including herniated intervertebral disc) because of the potential for hemorrhage and neurological deterioration, and because of excessive bleeding at the surgical site should surgical treatment be pursued. , epistaxis, hemangiosarcoma, head trauma). Animals with severe or poorly controlled asthma, or other types of moderate to severe pulmonary disease, may deteriorate with NSAID administration. Aspirin has been documented to exacerbate asthma in human patients; however, COX-2 specific NSAIDs did not result in worsening of clinical signs (West and Fernandez, 2003).

Aspirin is more COX-1 selective and can impair many components of mucosal defense and enhance leukocyte adherence within the gastric and mesenteric microcirculation (Wallace and Fiorucci, 2003). However, with chronic use of aspirin there is an adaptation of the gastric mucosa that is associated with a marked upregulation of COX-2 expression and lipoxin production. This lipoxin is specifically termed aspirin-triggered lipoxin (ATL). Aspirin is unique among current therapies because it acetylates COX-2, thereby enabling the biosynthesis of 15(R)hydroxyeicosatetraenoic acid (15(R)-HETE) from arachidonic acid, which is subsequently converted to ATL by 5-LOX.

Deracoxib/Deramax); whereas still another drug, acetaminophen, only weakly inhibits both COX-1 and COX-2, but is able to inhibit COX-3 activity preferentially (Botting, 2000). , 2000). , 2001). Most NSAIDs that inhibit COX have been shown to result in diversion of arachidonate to the 5-LOX pathway. , 2001). qxd 24 7/2/07 4:19 PM Page 24 PHARMACOLOGY AND DRUG DELIVERY leukotriene biosynthesis, which subsequently produces various eicosanoids, with LTB4 being the most notable potent mediator of inflammation.

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Zoo Animal and Wildlife Immobilization and Anesthesia by Gary West, Darryl Heard, Nigel Caulkett


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